PK11007 Vessel

PK11007 VesselPK11007 is an anti p53 drug that stabilizes wild type and mutant p53 via selective alkylation of two surface exposed cysteines without compromising its DNA binding activity. It exerts antitumor functions not only via reactivating p53 but also via other cellular mechanisms, such as increase of cellular ROS to toxic levels and activation of the UPR.

M and IC50 of 62

Sulfamerazine is a sulfonamide antibacterial

M in CHO-CFTR cell based assays

no activity to PDGFR

Corning This PYREX® replacement absorber is for the Arsine Generator System

Corning These PYREX® Graham condensers have a high surface area per unit length of the 500mm long jacket with a 24/40 Standard Taper outer joint at the top and a 24/40 Standard Taper inner joint at the bottom with a drip tip

GSK461364 inhibits purified Plk1 with Ki of 2

has antibacterial

accuracy and repeatability – with sd ≤ 1d combined with USP regulations conformity (Section 41 and 1251) make 4Y  balances

Hydroxyurea is an antineoplastic agent that inhibits DNA synthesis through the inhibition of ribonucleoside diphosphate reductase

AZ20 is a novel potent and selective inhibitor of ATR kinase with IC50 of 5 nM in a cell-free assay

29 and 495 nM for the recombinant BRAFV600E kinase domain