Tazemetostat (EPZ-6438) TC-Treated

Tazemetostat (EPZ-6438) TC-TreatedTazemetostat (EPZ 6438) is a potent, and selective EZH2 inhibitor with Ki and IC50 of 2. 5 nM and 11 nM in cell free assays, exhibiting a 35 fold selectivity versus EZH1 and >4,500 fold selectivity relative to 14 other HMTs.

24 Standard Taper stoppers

Less potent against Ron

is an inhibitor of X-linked inhibitor of apoptosis (XIAP) with IC50 of 4

Benzydamine hydrochloride is a topical nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory

limiting the spread of seizure activity and reducing seizure propagation

used in the treatment of hypertension

P5091(P005091) is a selective and potent inhibitor of ubiquitin-specific protease 7 (USP7) with EC50 of 4

is classified as a cysteine or a cysteine derivative that increases glutathione levels and is important for lung and brain function and liver detoxification

Hydroxypropyl cellulose (HPC) is a derivative of cellulose with both water solubility and organic solubility

Iopamidol is a non-ionic

copper-binding

(reversible) and mTOR with IC50 of 0